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Amyloidosis in adrenal incidentaloma: Finding by laparoscopic adrenalectomy



Sánchez-Castrejón E, Montalvo-Hernández J, Silva-Flores R, Pérez-Soto RH. Amyloidosis in adrenal incidentaloma: Finding by laparoscopic adrenalectomy. Am J Med Surg. 2021; 4(2). 9-12.

Abstract: An adrenal incidentaloma (AI) is an asymptomatic adrenal mass at least 1 cm in diameter detected on imaging studies performed for non-adrenal related disease. Amyloidosis is a rare disease and its presentation as an adrenal gland incidentaloma without systemic disease is exceptional. We present a 62-year-old woman with history of blunt abdominal trauma secondary to a vehicle accident 18 months ago. During her clinical assessment, an abdominal CT-scan was performed showing an AI with malignancy-suspicious features. Laparoscopic right adrenalectomy was performed. Histopathological examination exhibited amyloid infiltration in the hematoxylin and eosin (HE) staining, and it was confirmed by a positive Congo Red (CR) staining and a positive kappa and lambda chains immunohistochemistry.


Key Words: Adrenal incidentaloma, laparoscopic adrenalectomy.

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